Author(s): Pisters PW, Harrison LB, Leung DH, Woodruf JM, Casper ES
PURPOSE
This trial was performed to evaluate the impact of adjuvant brachytherapy on local and systemic recurrence rates in patients with soft tissue sarcoma.
PATIENTS AND METHODS
In a single-institution prospective randomized trial, 164 patients were randomized intraoperatively to receive either adjuvant brachytherapy (BRT) or no further therapy (no BRT) after complete resection of soft tissue sarcomas of the extremity or superficial trunk. The adjuvant radiation was administered by iridium-192 implant, which delivered 42 to 45 Gy over 4 to 6 days. The two study groups had comparable distributions of patient and tumor factors, including age, sex, tumor site, tumor size, and histologic type and grade.
Referred From: https://ascopubs.org/doi/10.1200/JCO.1996.14.3.859
Author(s): Pariente A
Author(s): Milic DJ, Rajkovic MM, Pejcic VD
Author(s): Mehdi S, Jalil M, Said B, Mohammed KL, Rahal M, et al.
Author(s): Marudanayagam R, Sandhu B, Perera MT, Bramhall SR, Mayer D
Author(s): Choi YY, Lee IS, Kim SJ, Kim JI, Choi KU
Author(s): Honoré C, Méeus P, Stoeckle E, Bonvalot S
Author(s): Okajima Y, Nishikawa M, Ohi M, Fukumoto Y, Kuroda K, et al.
Author(s): The ESMO/European Sarcoma Network Working Group
Author(s): Coindre JM, Terrier P, Bui NB, Bonichon F, Collin F, et al.
Author(s): Behranwala KA, A’Hern R, Omar AM, Thomas JM
Author(s): Dufresne A, Cassier P, Heudel P, Pissaloux D, Wang Q, et al.
