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EcommScripts.Buybox : null var Modal = EcommScripts ? EcommScripts.Modal : null if (weHasBrowserSupport && Buybox && Modal) { var modalID = "ecomm-modal_" + timestamp + "_" + index var modal = new Modal(modalID) modal.domEl.addEventListener("close", close) function close() { form.querySelector("button[type=submit]").focus() } var cartURL = "/cart" var cartModalURL = "/cart?messageOnly=1" form.setAttribute( "action", formAction.replace(cartURL, cartModalURL) ) var formSubmit = Buybox.interceptFormSubmit( Buybox.fetchFormAction(window.fetch), Buybox.triggerModalAfterAddToCartSuccess(modal), function() { form.removeEventListener("submit", formSubmit, false) form.setAttribute( "action", formAction.replace(cartModalURL, cartURL) ) form.submit() } ) form.addEventListener("submit", formSubmit, false) document.body.appendChild(modal.domEl) } else { console.log("binding failed:", weHasBrowserSupport, EcommScripts) } } } })() ReferencesEmery JL (1952) Chorionepithelioma in a newborn male child with hyperplasia of the interstitial cells of the testis. J Pathol Bacteriol 64: 735PubMed Google Scholar Kay S, Reed WG (1953) Chorioepithelioma of the lungs in female infant seven months old. Am J Pathol 2: 555 Google Scholar Buckell EWC, Owen TK (1954) Chorionepithelioma in mother and infant. J Obstet Gynaecol Br Emp 61: 329PubMed Google Scholar Mercer RD, Lammert AC, Anderson R (1958) Choriocarcinoma in mother and infant. JAMA 166: 482 Google Scholar Daamen CBF, Blown GWD, Westerbeek AJ (1961) Chorionepithelioma in mother and child. J Obstet Gynaecol Br Commonw 68: 144 Google Scholar Witzleben CL, Bruninga G (1968) Infantile choriocarcinoma: a characteristic syndrome. J Pediatr 73: 374PubMed Google Scholar Kelly DL, Kushner J, McLean WT (1971) Neonatal intracranial choriocarcinoma. J Neurosurg 35: 465PubMed Google Scholar Nieuwenhuijzen A, Kruseman AC, Van Lent M, Blom AH, Lauw GP (1977) Choriocarcinoma in mother and child identified by immunoenzyme histochemistry. Am J Clin Pathol 67: 279PubMed Google Scholar Kalifa C, Brule F, Baillif P, Caillaud JM, Schweisguth O (1981) Metastases chez un nourisson d'un choriocarcinome placentaire. Arch Fr Pédiatr 38: 351 Google Scholar Aozasa K, Ito H, Kohro T, Ha K, Nakamura M, Okada A (1981) Choriocarcinoma in infant and mother. Acta Pathol Jpn 31: 317PubMed Google Scholar Tsukamoto N, Matsumura M, Matukuma K, Kamura T, Bab K (1986) Choriocarcinoma in mother and fetus. Gynecol Oncol 24: 113PubMed Google Scholar Avril MF, Mathieu A, Kalifa C, Caillou C (1986) Infantile choriocarcinoma with cutaneous tumors. J Am Acad Dermatol 14: 918PubMed Google Scholar Flam F, Lundstrom V, Silfversward C (1989) Choriocarcinoma in mother and child. Case report. Br J Obstet Gynecol 96: 241 Google Scholar Chandra SA, Gilbert EF, Viseskul C, Strother CM, Haning RV, Javid MJ (1990) Neonatal intracranial choriocarcinoma. Arch Pathol Lab Med 114: 1079PubMed Google Scholar Fraser GC, Blair GK, Hemming A, Murphy JJ, Rogers P (1992) The treatment of simultaneous choriocarcinoma in mother and baby. J Pediatr Surg 27: 1318PubMed Google Scholar Brewer JI, Mazur MT (1981) Gestational choriocarcinoma. Its origin in the placenta during a seeminly normal pregnancy. Am J Surg Pathol 5: 267PubMed Google Scholar Grimelli KM, Colleti PM, Beck S (1988) Metastatic choriocarcinoma simulating anteriovenous malformation on chest radiography and dynamic CT. J Comput Assist Tomogr 12: 317PubMed Google Scholar Green JD, Carden TS, Hammond CB, Johnsrude IS (1973) Angiographic demonstration of arteriovenous shunts in pulmonary metastatic choriocarcinoma. Radiology 108: 67PubMed Google Scholar Adler J, Goodgold M, Mitty H, Gordon D, Kinkhabwala M (1978) Arteriovenous shunts involving the liver. Radiology 129: 315PubMed Google Scholar Matsunaga N, Hayashi K, Futagawa S et al (1989) Primary choriocarcinoma of the stomach presenting as gastrointestinal hemorrhage: report of a case. Radiat Med (Tokyo) 7: 220 Google Scholar McHugh K, Burrows PE (1992) Infantile hepatic hemangioendothelioma: significance of portal venous and systemic collateral arterial supply. J Vasc Intervent Radiol 3: 337 Google Scholar Bates SM, Keller MS, Ramos IM, Carter D, Taylor KJW (1990) Hepatoblastoma: detection of tumor vascularity with duplex Doppler ultrasound. Radiology 176: 505PubMed Google Scholar Paltiel JH, Patriquin HB, Keller MS, Babcock DS, Leithiser RE (1992) Infantile hepatic hemangioma: Doppler ultrasound. Radiology 182: 735PubMed Google Scholar Download referencesAuthor informationAuthors and AffiliationsDepartment of Diagnostic Imaging, The Hospital for Sick Children, 555 University Avenue, M5G 1X8, Toronto, Ontario, CanadaL. Dautenhahn, P. S. Babyn & C. R. SmithAuthorsL. DautenhahnView author publicationsYou can also search for this author in PubMed Google ScholarP. S. BabynView author publicationsYou can also search for this author in PubMed Google ScholarC. R. SmithView author publicationsYou can also search for this author in PubMed Google ScholarRights and permissionsReprints and PermissionsAbout this articleCite this articleDautenhahn, L., Babyn, P.S. & Smith, C.R. Metastatic choriocarcinoma in an infant: Imaging appearance. Pediatr Radiol 23, 597–600 (1993). https://doi.org/10.1007/BF02014976Download citationReceived: 19 July 1993Accepted: 04 October 1993Issue Date: December 1993DOI: https://doi.org/10.1007/BF02014976">

Metastatic choriocarcinoma in an infant: imaging appearance

Author(s): Dautenhahn L, Babyn PS, Smith CR

Abstract

Metastatic choriocarcinoma is unusual in infancy and considered to be due to metastases from the placenta. Only fifteen cases have been previously reported. We present an unusual case of hepatic, pulmonary, and axillary lymph node metastases from choriocarcinoma in a 3-month-old female. Several of the lesions had large vascular channels identified by computed tomography and sonography with color and duplex Doppler.

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Emery JL (1952) Chorionepithelioma in a newborn male child with hyperplasia of the interstitial cells of the testis. J Pathol Bacteriol 64: 735

PubMed Google Scholar

Kay S, Reed WG (1953) Chorioepithelioma of the lungs in female infant seven months old. Am J Pathol 2: 555

Google Scholar

Buckell EWC, Owen TK (1954) Chorionepithelioma in mother and infant. J Obstet Gynaecol Br Emp 61: 329

PubMed Google Scholar

Mercer RD, Lammert AC, Anderson R (1958) Choriocarcinoma in mother and infant. JAMA 166: 482

Google Scholar

Daamen CBF, Blown GWD, Westerbeek AJ (1961) Chorionepithelioma in mother and child. J Obstet Gynaecol Br Commonw 68: 144

Google Scholar

Witzleben CL, Bruninga G (1968) Infantile choriocarcinoma: a characteristic syndrome. J Pediatr 73: 374

PubMed Google Scholar

Kelly DL, Kushner J, McLean WT (1971) Neonatal intracranial choriocarcinoma. J Neurosurg 35: 465

PubMed Google Scholar

Nieuwenhuijzen A, Kruseman AC, Van Lent M, Blom AH, Lauw GP (1977) Choriocarcinoma in mother and child identified by immunoenzyme histochemistry. Am J Clin Pathol 67: 279

PubMed Google Scholar

Kalifa C, Brule F, Baillif P, Caillaud JM, Schweisguth O (1981) Metastases chez un nourisson d'un choriocarcinome placentaire. Arch Fr Pédiatr 38: 351

Google Scholar

Aozasa K, Ito H, Kohro T, Ha K, Nakamura M, Okada A (1981) Choriocarcinoma in infant and mother. Acta Pathol Jpn 31: 317

PubMed Google Scholar

Tsukamoto N, Matsumura M, Matukuma K, Kamura T, Bab K (1986) Choriocarcinoma in mother and fetus. Gynecol Oncol 24: 113

PubMed Google Scholar

Avril MF, Mathieu A, Kalifa C, Caillou C (1986) Infantile choriocarcinoma with cutaneous tumors. J Am Acad Dermatol 14: 918

PubMed Google Scholar

Flam F, Lundstrom V, Silfversward C (1989) Choriocarcinoma in mother and child. Case report. Br J Obstet Gynecol 96: 241

Google Scholar

Chandra SA, Gilbert EF, Viseskul C, Strother CM, Haning RV, Javid MJ (1990) Neonatal intracranial choriocarcinoma. Arch Pathol Lab Med 114: 1079

PubMed Google Scholar

Fraser GC, Blair GK, Hemming A, Murphy JJ, Rogers P (1992) The treatment of simultaneous choriocarcinoma in mother and baby. J Pediatr Surg 27: 1318

PubMed Google Scholar

Brewer JI, Mazur MT (1981) Gestational choriocarcinoma. Its origin in the placenta during a seeminly normal pregnancy. Am J Surg Pathol 5: 267

PubMed Google Scholar

Grimelli KM, Colleti PM, Beck S (1988) Metastatic choriocarcinoma simulating anteriovenous malformation on chest radiography and dynamic CT. J Comput Assist Tomogr 12: 317

PubMed Google Scholar

Green JD, Carden TS, Hammond CB, Johnsrude IS (1973) Angiographic demonstration of arteriovenous shunts in pulmonary metastatic choriocarcinoma. Radiology 108: 67

PubMed Google Scholar

Adler J, Goodgold M, Mitty H, Gordon D, Kinkhabwala M (1978) Arteriovenous shunts involving the liver. Radiology 129: 315

PubMed Google Scholar

Matsunaga N, Hayashi K, Futagawa S et al (1989) Primary choriocarcinoma of the stomach presenting as gastrointestinal hemorrhage: report of a case. Radiat Med (Tokyo) 7: 220

Google Scholar

McHugh K, Burrows PE (1992) Infantile hepatic hemangioendothelioma: significance of portal venous and systemic collateral arterial supply. J Vasc Intervent Radiol 3: 337

Google Scholar

Bates SM, Keller MS, Ramos IM, Carter D, Taylor KJW (1990) Hepatoblastoma: detection of tumor vascularity with duplex Doppler ultrasound. Radiology 176: 505

PubMed Google Scholar

Paltiel JH, Patriquin HB, Keller MS, Babcock DS, Leithiser RE (1992) Infantile hepatic hemangioma: Doppler ultrasound. Radiology 182: 735

PubMed Google Scholar

Download references

Author informationAuthors and AffiliationsAuthorsL. DautenhahnView author publicationsP. S. BabynView author publicationsC. R. SmithView author publicationsRights and permissions

Reprints and Permissions

About this articleCite this article

Dautenhahn, L., Babyn, P.S. & Smith, C.R. Metastatic choriocarcinoma in an infant: Imaging appearance. Pediatr Radiol 23, 597–600 (1993). https://doi.org/10.1007/BF02014976

Download citation

Received: 19 July 1993

Accepted: 04 October 1993

Issue Date: December 1993

DOI: https://doi.org/10.1007/BF02014976

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