The efficacy of hyperbaric oxygen therapy in the treatment of radiation-induced late side effects

Author(s): Bui QC, Lieber M, Withers HR, Corson K, Van Rijnsoever M, et al.



We investigated the efficacy of hyperbaric oxygen therapy (HBOT) in the management of patients with radiation-induced late side effects, the majority of whom had failed previous interventions.

Methods and materials

Of 105 eligible subjects, 30 had either died or were not contactable, leaving 75 who qualified for inclusion in this retrospective study. Patients answered a questionnaire documenting symptom severity before and after treatment (using Radiation Therapy Oncology Group criteria), duration of improvement, relapse incidence, and HBOT-related complications.

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