Trends in childhood rhab domyosarcoma incidence and survival in the United States 1975-2005

Author(s): Ognjanovic S, Linabery AM, Charbonneau B, Ross JA



Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and adolescents aged <20 years; its etiology remains largely unknown. It is believed that embryonal (ERMS) and alveolar rhabdomyosarcoma (ARMS), the most common subtypes, arise through distinct biologic mechanisms. The authors of this report evaluated incidence and survival trends by RMS demographic subgroups to inform future etiologic hypotheses.


Incidence and survival trends in RMS among children and adolescents aged <20 years were analyzed using data from the Surveillance, Epidemiology, and End Results Program. Frequencies, age-adjusted incidence and survival rates, and joinpoint regression results, including annual percentage change (APC) and 95% confidence interval (CI), were calculated.

Similar Articles

Soft tissue sarcoma of the hand in children: Clinical outcome and management

Author(s): Gross E, Rao BN, Pappo AS, Michalkiewicz E, Hudson MM, et al.

Tumeurs de la main chez l’enfant

Author(s): Salazard B, Philandrianos C

Imaging of the pediatric hand: Soft tissue abnormalities

Author(s): Jimenez RM1, Jaramillo D, Connolly SA

Soft tissue masses in children

Author(s): Navarro OM

Early life factors and risk of childhood rhabdomyosarcoma

Author(s): Shrestha A, Ritz B, Ognjanovic S, Lombardi CA, Wilhelm M, et al.

Soft-tissue sarcomas of the extremities in patients of pediatric age

Author(s): Casanova M, Meazza C, Gronchi A, Fiore M, Zaffignani E, et al.