Recommended Conferences

Genetic Engineering and Gene Therapy

Paris, France

Human Genetics and Genetic Disorders

Miami, USA

Tissue Engineering and Regenerative Medicine

Chicago, USA
Related Subjects
 

Bladder cancer biomarkers: review and update

Author(s): Ghafouri-Fard S,Nekoohesh L, Motevaseli E

Abstract

As the recurrence and mortality rates of bladder cancer are high, research is needed to find suitable biomarkers for early detection, evaluation of prognosis, and surveillance of drug responses. We performed a computerized search of the Medline/PubMed databases with the key words bladder cancer, biomarker, early detection, prognosis and drug response. Several markers were identified at DNA, RNA and protein levels with different sensitivities and specificities. Only a few of the potential bladder cancer biomarkers have been approved for clinical use. Efforts now should be concentrated on finding a panel of markers with acceptable sensitivity and specificity for early detection of bladder cancer.

Similar Articles

Recent advances in the diagnosis and treatment of bladder cancer

Author(s): Cheung G,Sahai A, Billia M, Dasgupta P, Khan MS

Primary bladder preservation treatment for urothelial bladder cancer

Author(s): Biagioli MC, Fernandez DC, Spiess PE, Wilder RB

Prediction of muscle-invasive bladder cancer using urinary proteomics

Author(s): Schiffer E,Vlahou A, Petrolekas A, Stravodimos K, Tauber R, et al.

Making sense of cancer genomic data

Author(s): Chin L, Hahn WC, Getz G, Meyerson M

Principles and methods of integrative genomic analyses in cancer

Author(s): Kristensen VN,Lingjærde OC,Russnes HG,Vollan HK,Frigessi A, et al.

affy--analysis of Affymetrix GeneChip data at the probe level

Author(s): Gautier L, Cope L, Bolstad BM, Irizarry RA

Biomarkers for bladder cancer aggressiveness

Author(s): Frantzi M,Makridakis M, Vlahou A

Gene profiling, biomarkers and pathways characterizing HCV-related hepatocellular carcinoma

Author(s): De Giorgi V, Monaco A, Worchech A, Tornesello M, Izzo F, et al.

The double bromodomain protein Brd2 promotes B cell expansion and mitogenesis

Author(s): Belkina AC, Blanton WP, Nikolajczyk BS, Denis GV

Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer

Author(s): Wyce A,Degenhardt Y, Bai Y, Le B, Korenchuk S, et al.

A UPF3-mediated regulatory switch that maintains RNA surveillance

Author(s): Chan WK,Bhalla AD, Le Hir H, Nguyen LS, Huang L, et al.

Targeted therapies in urothelial carcinoma

Author(s): Ghosh M,Brancato SJ, Agarwal PK, Apolo AB

Gene expression profiling and pathway analysis of superficial bladder cancer in rats

Author(s): Arum CJ,Anderssen E, Tømmerås K, Lundgren S, Chen D, et al.

Activation of RAS family genes in urothelial carcinoma

Author(s): Boulalas I,Zaravinos A, Karyotis I, Delakas D, Spandidos DA

Ras mutation cooperates with ß-catenin activation to drive bladder tumourigenesis

Author(s): Ahmad I, Patel R, Liu Y, Singh LB, Taketo MM, et al.

Ras in cancer and developmental diseases

Author(s): Fernández-Medarde A, Santos E